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Antibody Targeting of “Steady-State” Dendritic Cells Induces Tolerance Mediated by Regulatory T Cells

Dendritic cells (DCs) are often defined as pivotal inducers of immunity, but these proinflammatory properties only develop after stimulation or ex vivo manipulation of DCs. Under non-inflammatory conditions in vivo, DCs are embedded into a tissue environment and encounter a plethora of self-antigens...

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Detalles Bibliográficos
Autores principales: Mahnke, Karsten, Ring, Sabine, Enk, Alexander H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763042/
https://www.ncbi.nlm.nih.gov/pubmed/26941742
http://dx.doi.org/10.3389/fimmu.2016.00063