Visualizing Trimming Dependence of Biodistribution and Kinetics with Homo- and Heterogeneous N-Glycoclusters on Fluorescent Albumin

A series of N-glycans, each sequentially trimmed from biantennary sialoglycans, were homo- or heterogeneously clustered efficiently on fluorescent albumin using a method that combined strain-promoted alkyne-azide cyclization and 6π-azaelectrocyclization. Noninvasive in vivo kinetics and dissection a...

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Detalles Bibliográficos
Autores principales: Ogura, Akihiro, Tahara, Tsuyoshi, Nozaki, Satoshi, Morimoto, Koji, Kizuka, Yasuhiko, Kitazume, Shinobu, Hara, Mitsuko, Kojima, Soichi, Onoe, Hirotaka, Kurbangalieva, Almira, Taniguchi, Naoyuki, Watanabe, Yasuyoshi, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763176/
https://www.ncbi.nlm.nih.gov/pubmed/26902314
http://dx.doi.org/10.1038/srep21797

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