Trisulfate Disaccharide Decreases Calcium Overload and Protects Liver Injury Secondary to Liver Ischemia/Reperfusion

BACKGROUND: Ischemia and reperfusion (I/R) causes tissue damage and intracellular calcium levels are a factor of cell death. Sodium calcium exchanger (NCX) regulates calcium extrusion and Trisulfated Disaccharide (TD) acts on NCX decreasing intracellular calcium through the inhibition of the exchang...

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Detalles Bibliográficos
Autores principales: Vasques, Enio Rodrigues, Cunha, Jose Eduardo Monteiro, Coelho, Ana Maria Mendonca, Sampietre, Sandra N., Patzina, Rosely Antunes, Abdo, Emilio Elias, Nader, Helena B., Tersariol, Ivarne L. S., Lima, Marcelo Andrade, Godoy, Carlos M. G., Rodrigues, Tiago, Chaib, Eleazar, D’Albuquerque, Luiz A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763191/
https://www.ncbi.nlm.nih.gov/pubmed/26901764
http://dx.doi.org/10.1371/journal.pone.0149630

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