SGLT1 activity in lung alveolar cells of diabetic rats modulates airway surface liquid glucose concentration and bacterial proliferation

High glucose concentration in the airway surface liquid (ASL) is an important feature of diabetes that predisposes to respiratory infections. We investigated the role of alveolar epithelial SGLT1 activity on ASL glucose concentration and bacterial proliferation. Non-diabetic and diabetic rats were i...

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Detalles Bibliográficos
Autores principales: Oliveira, Tales Lyra, Candeia-Medeiros, Návylla, Cavalcante-Araújo, Polliane M., Melo, Igor Santana, Fávaro-Pípi, Elaine, Fátima, Luciana Alves, Rocha, Antônio Augusto, Goulart, Luiz Ricardo, Machado, Ubiratan Fabres, Campos, Ruy R., Sabino-Silva, Robinson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763199/
https://www.ncbi.nlm.nih.gov/pubmed/26902517
http://dx.doi.org/10.1038/srep21752

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