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Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy

Mesenchymal stem cells (MSCs)-based therapy provides a promising avenue for the management of peripheral arterial disease (PAD). However, engrafted MSCs are subjected to acute cell death in the ischemic microenvironment. Apelin has been shown to protect bone marrow MSCs against apoptosis although th...

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Detalles Bibliográficos
Autores principales: Liang, Dong, Han, Dong, Fan, Weiwei, Zhang, Ran, Qiao, Hongyu, Fan, Miaomiao, Su, Tao, Ma, Sai, Li, Xiujuan, Chen, Jiangwei, Wang, Yabin, Ren, Jun, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763210/
https://www.ncbi.nlm.nih.gov/pubmed/26902855
http://dx.doi.org/10.1038/srep21914