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One-step Conjugation of Glycyrrhetinic Acid to Cationic Polymers for High-performance Gene Delivery to Cultured Liver Cell

Gene therapies represent a promising therapeutic route for liver cancers, but major challenges remain in the design of safe and efficient gene-targeting delivery systems. For example, cationic polymers show good transfection efficiency as gene carriers, but are hindered by cytotoxicity and non-speci...

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Detalles Bibliográficos
Autores principales: Cong, Yue, Shi, Bingyang, Lu, Yiqing, Wen, Shihui, Chung, Roger, Jin, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763221/
https://www.ncbi.nlm.nih.gov/pubmed/26902258
http://dx.doi.org/10.1038/srep21891