Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma

Merkel cell carcinoma (MCC) is a virally associated cancer characterized by its aggressive behavior and strong immunogenicity. Both viral infection and malignant transformation induce expression of MHC class I chain-related protein (MIC) A and B, which signal stress to cells of the immune system via...

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Detalles Bibliográficos
Autores principales: Ritter, Cathrin, Fan, Kaiji, Paulson, Kelly G., Nghiem, Paul, Schrama, David, Becker, Jürgen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763224/
https://www.ncbi.nlm.nih.gov/pubmed/26902929
http://dx.doi.org/10.1038/srep21678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763224/
https://www.ncbi.nlm.nih.gov/pubmed/26902929
http://dx.doi.org/10.1038/srep21678

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