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Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin

Neurotensin (NT) triggers signaling in human colonic epithelial cells by activating the G protein-coupled receptor, the neurotensin receptor 1 (NTR1). Activated NTR1 traffics from the plasma membrane to early endosomes, and then recycles. Although sustained NT/NTR1 signaling requires efficient NTR1...

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Detalles Bibliográficos
Autores principales:	Law, Ivy Ka Man, Jensen, Dane, Bunnett, Nigel W., Pothoulakis, Charalabos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763298/ https://www.ncbi.nlm.nih.gov/pubmed/26902265 http://dx.doi.org/10.1038/srep22195

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