Cargando…

Implications of GABAergic Neurotransmission in Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized pathologically by the deposition of β-amyloid peptides (Aβ) and the accumulation of neurofibrillary tangles (NFTs) composed of hyper-phosphorylated tau. Regardless of the pathological hallmarks, synaptic dysfunction is widely accepted as a causal event in AD...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yanfang, Sun, Hao, Chen, Zhicai, Xu, Huaxi, Bu, Guojun, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763334/
https://www.ncbi.nlm.nih.gov/pubmed/26941642
http://dx.doi.org/10.3389/fnagi.2016.00031