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The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures
Obesity-induced inflammation caused by adipocyte-macrophage interactions plays a critical role in developing insulin resistance, and peroxisome proliferator-activated receptors (PPARs) regulate inflammatory gene expression in these cells. Recently, the soy isoflavone daidzein was reported to act as...
Autores principales: | Sakamoto, Yuri, Kanatsu, Junko, Toh, Mariko, Naka, Ayano, Kondo, Kazuo, Iida, Kaoruko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763373/ https://www.ncbi.nlm.nih.gov/pubmed/26901838 http://dx.doi.org/10.1371/journal.pone.0149676 |
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