Cargando…
Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature
Patient: Female, 43 Final Diagnosis: Primary breast lymphoma Symptoms: — Medication: — Clinical Procedure: CT scan • PET • chemotherapy • radiotherapy Specialty: Oncology OBJECTIVE: Rare disease BACKGROUND: Primary breast lymphoma (PBL) is an unusual clinical entity accounting for 0.4–0.5% of all br...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763798/ https://www.ncbi.nlm.nih.gov/pubmed/26893404 http://dx.doi.org/10.12659/AJCR.896264 |
_version_ | 1782417318102433792 |
---|---|
author | Jabbour, Gaby El-Mabrok, Gamela Al-Thani, Hassan El-Menyar, Ayman Hijji, Ibrahim Al Napaki, Sarbar |
author_facet | Jabbour, Gaby El-Mabrok, Gamela Al-Thani, Hassan El-Menyar, Ayman Hijji, Ibrahim Al Napaki, Sarbar |
author_sort | Jabbour, Gaby |
collection | PubMed |
description | Patient: Female, 43 Final Diagnosis: Primary breast lymphoma Symptoms: — Medication: — Clinical Procedure: CT scan • PET • chemotherapy • radiotherapy Specialty: Oncology OBJECTIVE: Rare disease BACKGROUND: Primary breast lymphoma (PBL) is an unusual clinical entity accounting for 0.4–0.5% of all breast neoplasms. The usual presentation includes a painless palpable mass similar to that of breast carcinoma. Diffuse large B-cell lymphoma (DLBCL) is the most common identifiable type of PBL based on the histopathological examination. CASE REPORT: We report an unusual case of a 43-year-old Indonesian woman who presented with a 7-month history of a painless mass in the left breast. A core needle biopsy revealed diffuse infiltration of large atypical lymphoid cells. The immunohistochemical biomarkers confirmed the diagnosis of a DLBCL. A bone scan showed no evidence of bone metastasis. It was treated non-surgically, based on the decision of the breast multidisciplinary team (MDT). The patient was treated with 4 cycles of combination chemotherapy with R-CODOX/IVAC. A follow-up PET scan revealed non-significant mild F-18 fluorodeoxyglucose (FDG) uptake at the periphery of the residual left breast mass, indicating a radiologically favorable response. CONCLUSIONS: Early and accurate diagnosis of PBL is crucial for selecting the appropriate MDT treatment strategies to avert potentially harmful surgical interventions. |
format | Online Article Text |
id | pubmed-4763798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-47637982016-03-08 Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature Jabbour, Gaby El-Mabrok, Gamela Al-Thani, Hassan El-Menyar, Ayman Hijji, Ibrahim Al Napaki, Sarbar Am J Case Rep Articles Patient: Female, 43 Final Diagnosis: Primary breast lymphoma Symptoms: — Medication: — Clinical Procedure: CT scan • PET • chemotherapy • radiotherapy Specialty: Oncology OBJECTIVE: Rare disease BACKGROUND: Primary breast lymphoma (PBL) is an unusual clinical entity accounting for 0.4–0.5% of all breast neoplasms. The usual presentation includes a painless palpable mass similar to that of breast carcinoma. Diffuse large B-cell lymphoma (DLBCL) is the most common identifiable type of PBL based on the histopathological examination. CASE REPORT: We report an unusual case of a 43-year-old Indonesian woman who presented with a 7-month history of a painless mass in the left breast. A core needle biopsy revealed diffuse infiltration of large atypical lymphoid cells. The immunohistochemical biomarkers confirmed the diagnosis of a DLBCL. A bone scan showed no evidence of bone metastasis. It was treated non-surgically, based on the decision of the breast multidisciplinary team (MDT). The patient was treated with 4 cycles of combination chemotherapy with R-CODOX/IVAC. A follow-up PET scan revealed non-significant mild F-18 fluorodeoxyglucose (FDG) uptake at the periphery of the residual left breast mass, indicating a radiologically favorable response. CONCLUSIONS: Early and accurate diagnosis of PBL is crucial for selecting the appropriate MDT treatment strategies to avert potentially harmful surgical interventions. International Scientific Literature, Inc. 2016-02-19 /pmc/articles/PMC4763798/ /pubmed/26893404 http://dx.doi.org/10.12659/AJCR.896264 Text en © Am J Case Rep, 2016 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License |
spellingShingle | Articles Jabbour, Gaby El-Mabrok, Gamela Al-Thani, Hassan El-Menyar, Ayman Hijji, Ibrahim Al Napaki, Sarbar Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature |
title | Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature |
title_full | Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature |
title_fullStr | Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature |
title_full_unstemmed | Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature |
title_short | Primary Breast Lymphoma in a Woman: A Case Report and Review of the Literature |
title_sort | primary breast lymphoma in a woman: a case report and review of the literature |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763798/ https://www.ncbi.nlm.nih.gov/pubmed/26893404 http://dx.doi.org/10.12659/AJCR.896264 |
work_keys_str_mv | AT jabbourgaby primarybreastlymphomainawomanacasereportandreviewoftheliterature AT elmabrokgamela primarybreastlymphomainawomanacasereportandreviewoftheliterature AT althanihassan primarybreastlymphomainawomanacasereportandreviewoftheliterature AT elmenyarayman primarybreastlymphomainawomanacasereportandreviewoftheliterature AT hijjiibrahimal primarybreastlymphomainawomanacasereportandreviewoftheliterature AT napakisarbar primarybreastlymphomainawomanacasereportandreviewoftheliterature |