Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies

Biliary atresia (BA) is classically described at the neonatal age. However, rare cases of BA in older infants have also been reported. We report four cases of late-onset BA in infants older than 4 weeks (3 males, 1 female), and describe the diagnostic and management difficulties. One of the cases ha...

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Autores principales: Fontenele, J.P.U., Schenka, A.A., Hessel, G., Jarry, V.M., Escanhoela, C.A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763814/
https://www.ncbi.nlm.nih.gov/pubmed/26840713
http://dx.doi.org/10.1590/1414-431X20154808
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author Fontenele, J.P.U.
Schenka, A.A.
Hessel, G.
Jarry, V.M.
Escanhoela, C.A.F.
author_facet Fontenele, J.P.U.
Schenka, A.A.
Hessel, G.
Jarry, V.M.
Escanhoela, C.A.F.
author_sort Fontenele, J.P.U.
collection PubMed
description Biliary atresia (BA) is classically described at the neonatal age. However, rare cases of BA in older infants have also been reported. We report four cases of late-onset BA in infants older than 4 weeks (3 males, 1 female), and describe the diagnostic and management difficulties. One of the cases had a late-onset (29 weeks) presentation with a successful surgical procedure. We highlight the importance of this unusual differential diagnosis in infants with cholestatic syndrome, who may benefit from Kasai surgery, regardless of age.
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spelling pubmed-47638142016-03-07 Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies Fontenele, J.P.U. Schenka, A.A. Hessel, G. Jarry, V.M. Escanhoela, C.A.F. Braz J Med Biol Res Case Report Biliary atresia (BA) is classically described at the neonatal age. However, rare cases of BA in older infants have also been reported. We report four cases of late-onset BA in infants older than 4 weeks (3 males, 1 female), and describe the diagnostic and management difficulties. One of the cases had a late-onset (29 weeks) presentation with a successful surgical procedure. We highlight the importance of this unusual differential diagnosis in infants with cholestatic syndrome, who may benefit from Kasai surgery, regardless of age. Associação Brasileira de Divulgação Científica 2016-02-02 /pmc/articles/PMC4763814/ /pubmed/26840713 http://dx.doi.org/10.1590/1414-431X20154808 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fontenele, J.P.U.
Schenka, A.A.
Hessel, G.
Jarry, V.M.
Escanhoela, C.A.F.
Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies
title Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies
title_full Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies
title_fullStr Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies
title_full_unstemmed Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies
title_short Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies
title_sort clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763814/
https://www.ncbi.nlm.nih.gov/pubmed/26840713
http://dx.doi.org/10.1590/1414-431X20154808
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