Cargando…
Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates
11 FRET-based fluorogenic substrates were constructed using the pentapeptide template Asp-Glu-X(2)-Asp-X(1)′, and evaluated with caspase-3, caspase-7 and cathepsin B. The sequence Asp-Glu-Pro-Asp-Ser was able to selectively quantify caspase-3 activity in vitro without notable caspase-7 and cathepsin...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763880/ https://www.ncbi.nlm.nih.gov/pubmed/26726961 http://dx.doi.org/10.1039/c5mb00730e |