Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration

Ranibizumab is a monoclonal antibody fragment that inhibits angiogenesis by inhibiting vascular endothelial growth factor A, used as a treatment for patients with wet aged-related macular degeneration (ARMD). Adverse effects from intravitreal Ranibizumab injections are well recognised. Macular hole...

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Detalles Bibliográficos
Autores principales: Mukherjee, Chandoshi, Mitra, Arijit, Kumar, N. Ajith, Elsherbiny, Samer, Lip, Peck Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763958/
https://www.ncbi.nlm.nih.gov/pubmed/26962382
http://dx.doi.org/10.2174/1874364101509010177
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author Mukherjee, Chandoshi
Mitra, Arijit
Kumar, N. Ajith
Elsherbiny, Samer
Lip, Peck Lin
author_facet Mukherjee, Chandoshi
Mitra, Arijit
Kumar, N. Ajith
Elsherbiny, Samer
Lip, Peck Lin
author_sort Mukherjee, Chandoshi
collection PubMed
description Ranibizumab is a monoclonal antibody fragment that inhibits angiogenesis by inhibiting vascular endothelial growth factor A, used as a treatment for patients with wet aged-related macular degeneration (ARMD). Adverse effects from intravitreal Ranibizumab injections are well recognised. Macular hole formation following Ranibizumab injection is a complication that has been recently reported in few case reports. We present a larger case series of five patients, who developed full thickness macular holes (FTMH) after intravitreal Ranibizumab injections for treatment of wet ARMD that we were aware of between 2009 and 2013.
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spelling pubmed-47639582016-03-09 Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration Mukherjee, Chandoshi Mitra, Arijit Kumar, N. Ajith Elsherbiny, Samer Lip, Peck Lin Open Ophthalmol J Article Ranibizumab is a monoclonal antibody fragment that inhibits angiogenesis by inhibiting vascular endothelial growth factor A, used as a treatment for patients with wet aged-related macular degeneration (ARMD). Adverse effects from intravitreal Ranibizumab injections are well recognised. Macular hole formation following Ranibizumab injection is a complication that has been recently reported in few case reports. We present a larger case series of five patients, who developed full thickness macular holes (FTMH) after intravitreal Ranibizumab injections for treatment of wet ARMD that we were aware of between 2009 and 2013. Bentham Open 2015-12-31 /pmc/articles/PMC4763958/ /pubmed/26962382 http://dx.doi.org/10.2174/1874364101509010177 Text en © Mukherjee et al.; Licensee Bentham Open. https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Mukherjee, Chandoshi
Mitra, Arijit
Kumar, N. Ajith
Elsherbiny, Samer
Lip, Peck Lin
Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration
title Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration
title_full Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration
title_fullStr Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration
title_full_unstemmed Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration
title_short Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration
title_sort macular hole formation after intravitreal ranibizumab injection in wet age-related macular degeneration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763958/
https://www.ncbi.nlm.nih.gov/pubmed/26962382
http://dx.doi.org/10.2174/1874364101509010177
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