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Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate
AIM: This study evaluates the disinfection of dentinal tubules using Propolis, Azadirachta indica (alcoholic and aqueous extracts), 2% chlorhexidine gel and calcium hydroxide against Candida albicans biofilm formed on tooth substrate. MATERIALS & METHOD: One hundred and five human teeth were inf...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Bentham Science Publishers
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763964/ https://www.ncbi.nlm.nih.gov/pubmed/26962368 http://dx.doi.org/10.2174/1874210601509010369 |
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author | Joy Sinha, Dakshita Garg, Paridhi Verma, Anurag Malik, Vibha Maccune, Edgar Richard Vasudeva, Agrima |
author_facet | Joy Sinha, Dakshita Garg, Paridhi Verma, Anurag Malik, Vibha Maccune, Edgar Richard Vasudeva, Agrima |
author_sort | Joy Sinha, Dakshita |
collection | PubMed |
description | AIM: This study evaluates the disinfection of dentinal tubules using Propolis, Azadirachta indica (alcoholic and aqueous extracts), 2% chlorhexidine gel and calcium hydroxide against Candida albicans biofilm formed on tooth substrate. MATERIALS & METHOD: One hundred and five human teeth were infected with Candida albicans for 2 days. Samples were divided into 7 groups. Group I- Propolis, Group II- Alcoholic extract of Azadirachta indica, Group III- Aqueous extract of Azadirachta indica, Group IV- 2% Chlorhexidine, Group V- Calcium hydroxide, Group VI- Ethanol and Group VII- Saline (negative control). At the end of 1,3 and 5 days, the antimicrobial efficacy of medicaments against Candida albicans was assessed at the depths of 200 µm and 400 µm. RESULTS: The overall percentage inhibition of fungal growth (at 200 µm and 400 µm depth) was 99.2% with 2% chlorhexidine gel. There was no statistical difference between propolis, alcoholic extract of Azadirachta indica (neem) and 2% chlorhexidine. CONCLUSION: Propolis and alcoholic extract of Azadirachta indica performed equally well as that of 2% Chlorhexidine. |
format | Online Article Text |
id | pubmed-4763964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Bentham Science Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-47639642016-03-09 Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate Joy Sinha, Dakshita Garg, Paridhi Verma, Anurag Malik, Vibha Maccune, Edgar Richard Vasudeva, Agrima Open Dent J Article AIM: This study evaluates the disinfection of dentinal tubules using Propolis, Azadirachta indica (alcoholic and aqueous extracts), 2% chlorhexidine gel and calcium hydroxide against Candida albicans biofilm formed on tooth substrate. MATERIALS & METHOD: One hundred and five human teeth were infected with Candida albicans for 2 days. Samples were divided into 7 groups. Group I- Propolis, Group II- Alcoholic extract of Azadirachta indica, Group III- Aqueous extract of Azadirachta indica, Group IV- 2% Chlorhexidine, Group V- Calcium hydroxide, Group VI- Ethanol and Group VII- Saline (negative control). At the end of 1,3 and 5 days, the antimicrobial efficacy of medicaments against Candida albicans was assessed at the depths of 200 µm and 400 µm. RESULTS: The overall percentage inhibition of fungal growth (at 200 µm and 400 µm depth) was 99.2% with 2% chlorhexidine gel. There was no statistical difference between propolis, alcoholic extract of Azadirachta indica (neem) and 2% chlorhexidine. CONCLUSION: Propolis and alcoholic extract of Azadirachta indica performed equally well as that of 2% Chlorhexidine. Bentham Science Publishers 2015-11-12 /pmc/articles/PMC4763964/ /pubmed/26962368 http://dx.doi.org/10.2174/1874210601509010369 Text en © Sinha et al.; Licensee Bentham Open. https://creativecommons.org/licenses/by/4.0/legalcode This is an open access articles licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided that the work is properly cited. |
spellingShingle | Article Joy Sinha, Dakshita Garg, Paridhi Verma, Anurag Malik, Vibha Maccune, Edgar Richard Vasudeva, Agrima Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate |
title | Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate |
title_full | Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate |
title_fullStr | Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate |
title_full_unstemmed | Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate |
title_short | Dentinal Tubule Disinfection with Propolis & Two Extracts of Azadirachta indica Against Candida albicans Biofilm Formed on Tooth Substrate |
title_sort | dentinal tubule disinfection with propolis & two extracts of azadirachta indica against candida albicans biofilm formed on tooth substrate |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763964/ https://www.ncbi.nlm.nih.gov/pubmed/26962368 http://dx.doi.org/10.2174/1874210601509010369 |
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