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Activating peptides for cellular uptake via polymerization into high density brushes

The utility of peptide therapeutics is thwarted by an inability to enter cells, preventing access to crucial intracellular targets. Herein, we describe a simple and potentially widely applicable solution involving the polymerization of a minimally modified amino acid sequence into a high density bru...

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Detalles Bibliográficos
Autores principales: Blum, Angela P., Kammeyer, Jacquelin K., Gianneschi, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763988/
https://www.ncbi.nlm.nih.gov/pubmed/26925209
http://dx.doi.org/10.1039/c5sc03417e