Continuous AMD3100 Treatment Worsens Renal Fibrosis through Regulation of Bone Marrow Derived Pro-Angiogenic Cells Homing and T-Cell-Related Inflammation

AMD3100 is a small molecule inhibitor of chemokine receptor type 4 (CXCR4), which is located in the cell membranes of CD34+ cells and a variety of inflammatory cells and has been reported to reduce organ fibrosis in the lung, liver and myocardium. However, the effect of AMD3100 on renal fibrosis is...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Juan, Zhu, Fengming, Wang, Xiaohui, Yao, Weiqi, Wang, Meng, Pei, Guangchang, Hu, Zhizhi, Guo, Yujiao, Zhao, Zhi, Wang, Pengge, Mou, Jingyi, Sun, Jie, Zeng, Rui, Xu, Gang, Liao, Wenhui, Yao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763993/
https://www.ncbi.nlm.nih.gov/pubmed/26900858
http://dx.doi.org/10.1371/journal.pone.0149926

Ejemplares similares

Ejemplares similares