Crystal structures of penicillin‐binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms

Penicillin‐binding protein 3 (PBP3) from Pseudomonas aeruginosa is the molecular target of β‐lactam‐based antibiotics. Structures of PBP3 in complexes with azlocillin and cefoperazone, which are in clinical use for the treatment of pseudomonad infections, have been determined to 2.0 Å resolution. To...

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Detalles Bibliográficos
Autores principales: Ren, Jingshan, Nettleship, Joanne E., Males, Alexandra, Stuart, David I., Owens, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764023/
https://www.ncbi.nlm.nih.gov/pubmed/26823174
http://dx.doi.org/10.1002/1873-3468.12054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764023/
https://www.ncbi.nlm.nih.gov/pubmed/26823174
http://dx.doi.org/10.1002/1873-3468.12054

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