Cargando…

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes

The possible contribution of HLA-DRB3, -DRB4, and -DRB5 alleles to type 1 diabetes risk and to insulin autoantibody (IAA), GAD65 (GAD autoantibody [GADA]), IA-2 antigen (IA-2A), or ZnT8 against either of the three amino acid variants R, W, or Q at position 325 (ZnT8RA, ZnT8WA, and ZnT8QA, respective...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Lue Ping, Alshiekh, Shehab, Zhao, Michael, Carlsson, Annelie, Elding Larsson, Helena, Forsander, Gun, Ivarsson, Sten A., Ludvigsson, Johnny, Kockum, Ingrid, Marcus, Claude, Persson, Martina, Samuelsson, Ulf, Örtqvist, Eva, Pyo, Chul-Woo, Nelson, Wyatt C., Geraghty, Daniel E., Lernmark, Åke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2016
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764147/ https://www.ncbi.nlm.nih.gov/pubmed/26740600 http://dx.doi.org/10.2337/db15-1115

Ejemplares similares

Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes
por: Zhao, Lue Ping, et al.
Publicado: (2019)

The KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes
por: Zhao, Lue Ping, et al.
Publicado: (2021)

High‐resolution genotyping indicates that children with type 1 diabetes and celiac disease share three HLA class II loci in DRB3, DRB4 and DRB5 genes
por: Alshiekh, Shehab, et al.
Publicado: (2020)

Zinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study
por: Delli, Ahmed J., et al.
Publicado: (2012)

High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
por: Paulsson, Johan F., et al.
Publicado: (2014)

Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01
por: Arribas-Layton, David, et al.
Publicado: (2020)

Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY: Lessons From a 5-Year Pediatric Swedish National Cohort Study
por: Carlsson, Annelie, et al.
Publicado: (2020)

Month of birth and the risk of developing type 1 diabetes among children in the Swedish national Better Diabetes Diagnosis Study
por: Hedlund, Emma, et al.
Publicado: (2022)

DRB1, DRB2 and DRB4 Are Required for Appropriate Regulation of the microRNA399/PHOSPHATE2 Expression Module in Arabidopsis thaliana
por: Pegler, Joseph L., et al.
Publicado: (2019)

Evidence for an association of HLA-DRB1*15 and DRB1*09 with leprosy and the impact of DRB1*09 on disease onset in a Chinese Han population
por: Zhang, Furen, et al.
Publicado: (2009)

HLA DRB101 and macrophagic myofasciitis
por: Guis, S, et al.
Publicado: (2003)

Association of HLA-DRB1*11 and HLA-DRB1*12 gene polymorphism with COVID-19 in Burkina Faso
por: Ouedraogo, Alfred Rakissida, et al.
Publicado: (2023)

Multiple Sclerosis Risk Variant HLA-DRB1*1501 Associates with High Expression of DRB1 Gene in Different Human Populations
por: Alcina, Antonio, et al.
Publicado: (2012)

Human Leukocyte Antigen (HLA)-DRB1*15:01 and HLA-DRB5*01:01 Present Complementary Peptide Repertoires
por: Scholz, Erika Margaret, et al.
Publicado: (2017)

Anti-phosphatidylserine/prothrombin antibodies and thrombosis associate positively with HLA-DRB1*13 and negatively with HLA-DRB1*03 in SLE
por: Elbagir, Sahwa, et al.
Publicado: (2022)

Nine residues in HLA-DQ molecules determine with susceptibility and resistance to type 1 diabetes among young children in Sweden
por: Zhao, Lue Ping, et al.
Publicado: (2021)

Residual beta cell function at diagnosis of type 1 diabetes in children and adolescents varies with gender and season
por: Samuelsson, U, et al.
Publicado: (2013)

HLA-DRB1 genes and extraarticular rheumatoid arthritis
por: Roudier, Jean
Publicado: (2006)

Association of the HLA-DRB1 with Scleroderma in Chinese Population
por: He, Dongyi, et al.
Publicado: (2014)

Identification of HLA-DRB1 association to adalimumab immunogenicity
por: Liu, Mohan, et al.
Publicado: (2018)

A multicenter observational safety study in Swedish children and adolescents using insulin detemir for the treatment of type 1 diabetes
por: Carlsson, Annelie, et al.
Publicado: (2013)

HLA-DRB1(∗)0401 and HLA-DRB1(∗)0408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis
por: Hoffmann, Steve, et al.
Publicado: (2008)

HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA- DRB1*0301 (DR3) gene
Publicado: (1996)

DRB2 Is Required for MicroRNA Biogenesis in Arabidopsis thaliana
por: Eamens, Andrew L., et al.
Publicado: (2012)

Association between migraine and HLA–DRB1 gene polymorphisms
por: Rainero, I., et al.
Publicado: (2005)

Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping
por: Ringquist, Steven, et al.
Publicado: (2013)

Association of HLA DRB variants to genetic predisposition to rheumatoid arthritis
por: Jarullah, Bushra S
Publicado: (2014)

Diversity of Extended HLA-DRB1 Haplotypes in the Finnish Population
por: Wennerström, Annika, et al.
Publicado: (2013)

The Protective Role of HLA-DRB1(∗)13 in Autoimmune Diseases
por: Bettencourt, Andreia, et al.
Publicado: (2015)

Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis
por: Zong, Wenkai, et al.
Publicado: (2016)

Structure based selection of Human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis
por: Misra, Maneesh K., et al.
Publicado: (2018)

Human Leukocyte Antigen Association Study Reveals DRB1*04:02 Effects Additional to DRB1*07:01 in Anti-LGI1 Encephalitis
por: Peris Sempere, Vicente, et al.
Publicado: (2022)

Association of Human Leukocyte Antigen DRB1*15 and DRB1*15:01 Polymorphisms with Response to Immunosuppressive Therapy in Patients with Aplastic Anemia: A Meta-Analysis
por: Liu, Shan, et al.
Publicado: (2016)

Association of HLA-DR2-Related Haplotype (HLA-DRB5*01-DRB1*1501-DQB1*0602) in Patients with Multiple Sclerosis in Khuzestan Province
por: DELFAN, Nooshin, et al.
Publicado: (2021)

Modeling of PTPN22 and HLA-DRB1 susceptibility to rheumatoid arthritis
por: Gagnon, France, et al.
Publicado: (2007)

HLA-DRB1 encoded predisposition to rheumatoid arthritis: the anchor hypothesis
por: de Vries, N, et al.
Publicado: (2004)

Incomplete DRB4-dependence of the DCL4-mediated antiviral defense
por: Zhang, Xiaofeng, et al.
Publicado: (2016)

Association of Ovar‐DRB1 alleles with innate immune responses in sheep
por: Esmailnejad, Atefeh, et al.
Publicado: (2021)

In Silico Analysis: HLA-DRB1 Gene’s Variants and Their Clinical Impact
por: Hassan, Mohamed M., et al.
Publicado: (2023)

DRB1–environment interactions in multiple sclerosis etiology: results from two Swedish case–control studies
por: Hedström, Anna Karin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9t3iip47q9ipirtc9a2sv3lfnd