Andes Hantavirus-Infection of a 3D Human Lung Tissue Model Reveals a Late Peak in Progeny Virus Production Followed by Increased Levels of Proinflammatory Cytokines and VEGF-A

Andes virus (ANDV) causes hantavirus pulmonary syndrome (HPS), a severe acute disease with a 40% case fatality rate. Humans are infected via inhalation, and the lungs are severely affected during HPS, but little is known regarding the effects of ANDV-infection of the lung. Using a 3-dimensional air-...

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Detalles Bibliográficos
Autores principales: Sundström, Karin B., Nguyen Hoang, Anh Thu, Gupta, Shawon, Ahlm, Clas, Svensson, Mattias, Klingström, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764364/
https://www.ncbi.nlm.nih.gov/pubmed/26907493
http://dx.doi.org/10.1371/journal.pone.0149354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764364/
https://www.ncbi.nlm.nih.gov/pubmed/26907493
http://dx.doi.org/10.1371/journal.pone.0149354

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