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Andes Hantavirus-Infection of a 3D Human Lung Tissue Model Reveals a Late Peak in Progeny Virus Production Followed by Increased Levels of Proinflammatory Cytokines and VEGF-A
Andes virus (ANDV) causes hantavirus pulmonary syndrome (HPS), a severe acute disease with a 40% case fatality rate. Humans are infected via inhalation, and the lungs are severely affected during HPS, but little is known regarding the effects of ANDV-infection of the lung. Using a 3-dimensional air-...
Autores principales: | Sundström, Karin B., Nguyen Hoang, Anh Thu, Gupta, Shawon, Ahlm, Clas, Svensson, Mattias, Klingström, Jonas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764364/ https://www.ncbi.nlm.nih.gov/pubmed/26907493 http://dx.doi.org/10.1371/journal.pone.0149354 |
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