Cargando…
Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function
Mouse CA1 pyramidal neurons express apamin-sensitive SK2-containing channels in the post-synaptic membrane, positioned close to NMDA-type (N-methyl-D-aspartate) glutamate receptors. Activated by synaptically evoked NMDAR-dependent Ca(2+) influx, the synaptic SK2-containing channels modulate excitato...
Autores principales: | Kim, Gukhan, Luján, Rafael, Schwenk, Jochen, Kelley, Melissa H, Aguado, Carolina, Watanabe, Masahiko, Fakler, Bernd, Maylie, James, Adelman, John P |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764564/ https://www.ncbi.nlm.nih.gov/pubmed/26880549 http://dx.doi.org/10.7554/eLife.12637 |
Ejemplares similares
-
The SK2-Long Isoform Directs Synaptic Localization and Function of SK2-containing channels
por: Allen, Duane, et al.
Publicado: (2011) -
Localization of SK2 channels relative to excitatory synaptic sites in the mouse developing Purkinje cells
por: Ballesteros-Merino, Carmen, et al.
Publicado: (2014) -
Role of Palmitoylation of Postsynaptic Proteins in Promoting Synaptic Plasticity
por: Matt, Lucas, et al.
Publicado: (2019) -
Neural Palmitoyl-Proteomics Reveals Dynamic Synaptic Palmitoylation
por: Kang, Rujun, et al.
Publicado: (2008) -
Editorial: Role of Protein Palmitoylation in Synaptic Plasticity and Neuronal Differentiation
por: Yoshii, Akira, et al.
Publicado: (2020)