Cargando…
Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes
Messenger RNA localization is important for cell motility by local protein translation. However, while single mRNAs can be imaged and their movements tracked in single cells, it has not yet been possible to determine whether these mRNAs are actively translating. Therefore, we imaged single β-actin m...
Autores principales: | Katz, Zachary B, English, Brian P, Lionnet, Timothée, Yoon, Young J, Monnier, Nilah, Ovryn, Ben, Bathe, Mark, Singer, Robert H |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764586/ https://www.ncbi.nlm.nih.gov/pubmed/26760529 http://dx.doi.org/10.7554/eLife.10415 |
Ejemplares similares
-
RNA Polymerase II cluster dynamics predict mRNA output in living cells
por: Cho, Won-Ki, et al.
Publicado: (2016) -
Real-time observation of signal recognition particle binding to actively translating ribosomes
por: Noriega, Thomas R, et al.
Publicado: (2014) -
Structures of translationally inactive mammalian ribosomes
por: Brown, Alan, et al.
Publicado: (2018) -
Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch
por: Le, My-Tra, et al.
Publicado: (2017) -
Robust model-based analysis of single-particle tracking experiments with Spot-On
por: Hansen, Anders S, et al.
Publicado: (2018)