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Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice

Degenerative joint diseases such as osteoarthritis are characterised by aberrant region-specific bone formation and abnormal bone mineral content. A recent study suggested a role for the complement membrane attack complex in experimental models of osteoarthritis. Since CD59a is the principal regulat...

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Detalles Bibliográficos
Autores principales:	Bloom, Anja C., Collins, Fraser L., van't Hof, Rob J., Ryan, Elizabeth S., Jones, Emma, Hughes, Timothy R., Morgan, B. Paul, Erlandsson, Malin, Bokarewa, Maria, Aeschlimann, Daniel, Evans, Bronwen A.J., Williams, Anwen S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2016
Materias:	Original Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764651/ https://www.ncbi.nlm.nih.gov/pubmed/26721735 http://dx.doi.org/10.1016/j.bone.2015.12.014

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