Surface Proteoglycans as Mediators in Bacterial Pathogens Infections

Infectious diseases remain an important global health problem. The interaction of a wide range of pathogen bacteria with host cells from many different tissues is frequently mediated by proteoglycans. These compounds are ubiquitous complex molecules which are not only involved in adherence and colon...

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Detalles Bibliográficos
Autores principales: García, Beatriz, Merayo-Lloves, Jesús, Martin, Carla, Alcalde, Ignacio, Quirós, Luis M., Vazquez, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764700/
https://www.ncbi.nlm.nih.gov/pubmed/26941735
http://dx.doi.org/10.3389/fmicb.2016.00220
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author García, Beatriz
Merayo-Lloves, Jesús
Martin, Carla
Alcalde, Ignacio
Quirós, Luis M.
Vazquez, Fernando
author_facet García, Beatriz
Merayo-Lloves, Jesús
Martin, Carla
Alcalde, Ignacio
Quirós, Luis M.
Vazquez, Fernando
author_sort García, Beatriz
collection PubMed
description Infectious diseases remain an important global health problem. The interaction of a wide range of pathogen bacteria with host cells from many different tissues is frequently mediated by proteoglycans. These compounds are ubiquitous complex molecules which are not only involved in adherence and colonization, but can also participate in other steps of pathogenesis. To overcome the problem of microbial resistance to antibiotics new therapeutic agents could be developed based on the characteristics of the interaction of pathogens with proteoglycans.
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spelling pubmed-47647002016-03-03 Surface Proteoglycans as Mediators in Bacterial Pathogens Infections García, Beatriz Merayo-Lloves, Jesús Martin, Carla Alcalde, Ignacio Quirós, Luis M. Vazquez, Fernando Front Microbiol Microbiology Infectious diseases remain an important global health problem. The interaction of a wide range of pathogen bacteria with host cells from many different tissues is frequently mediated by proteoglycans. These compounds are ubiquitous complex molecules which are not only involved in adherence and colonization, but can also participate in other steps of pathogenesis. To overcome the problem of microbial resistance to antibiotics new therapeutic agents could be developed based on the characteristics of the interaction of pathogens with proteoglycans. Frontiers Media S.A. 2016-02-24 /pmc/articles/PMC4764700/ /pubmed/26941735 http://dx.doi.org/10.3389/fmicb.2016.00220 Text en Copyright © 2016 García, Merayo-Lloves, Martin, Alcalde, Quirós and Vazquez. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
García, Beatriz
Merayo-Lloves, Jesús
Martin, Carla
Alcalde, Ignacio
Quirós, Luis M.
Vazquez, Fernando
Surface Proteoglycans as Mediators in Bacterial Pathogens Infections
title Surface Proteoglycans as Mediators in Bacterial Pathogens Infections
title_full Surface Proteoglycans as Mediators in Bacterial Pathogens Infections
title_fullStr Surface Proteoglycans as Mediators in Bacterial Pathogens Infections
title_full_unstemmed Surface Proteoglycans as Mediators in Bacterial Pathogens Infections
title_short Surface Proteoglycans as Mediators in Bacterial Pathogens Infections
title_sort surface proteoglycans as mediators in bacterial pathogens infections
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764700/
https://www.ncbi.nlm.nih.gov/pubmed/26941735
http://dx.doi.org/10.3389/fmicb.2016.00220
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