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miRNA-221-3p Enhances the Secretion of Interleukin-4 in Mast Cells through the Phosphatase and Tensin Homolog/p38/Nuclear Factor-kappaB Pathway

Mast cells play a central role in asthma. Moreover, serum miRNA-221-3p (miR-221) has been shown to be markedly increased in children with asthma. In the current study, we aimed to examine miR-221 expression in an asthma model and elucidate the mechanisms regulating interleukin (IL)-4 secretion in ma...

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Detalles Bibliográficos
Autores principales:	Zhou, Yao, Yang, Qianyuan, Xu, Hong, Zhang, Jiamin, Deng, Huan, Gao, Haiyan, Yang, Jin, Zhao, Deyu, Liu, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764704/ https://www.ncbi.nlm.nih.gov/pubmed/26901347 http://dx.doi.org/10.1371/journal.pone.0148821

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