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Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets
Malignant gliomas are aggressive brain tumors with limited therapeutic options, possibly because of highly tumorigenic subpopulations of glioma stem cells. These cells require specific microenvironments to maintain their “stemness,” described as perivascular and hypoxic niches. Each of those niches...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764748/ https://www.ncbi.nlm.nih.gov/pubmed/26977157 http://dx.doi.org/10.1155/2016/5728438 |