Novel Y-chromosomal microdeletions associated with non-obstructive azoospermia uncovered by high throughput sequencing of sequence-tagged sites (STSs)

Y-chromosomal microdeletion (YCM) serves as an important genetic factor in non-obstructive azoospermia (NOA). Multiplex polymerase chain reaction (PCR) is routinely used to detect YCMs by tracing sequence-tagged sites (STSs) in the Y chromosome. Here we introduce a novel methodology in which we sequ...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Li, Zesong, Su, Zheng, Zhang, Junjie, Li, Honggang, Xie, Jun, Xu, Hanshi, Jiang, Tao, Luo, Liya, Zhang, Ruifang, Zeng, Xiaojing, Xu, Huaiqian, Huang, Yi, Mou, Lisha, Hu, Jingchu, Qian, Weiping, Zeng, Yong, Zhang, Xiuqing, Xiong, Chengliang, Yang, Huanming, Kristiansen, Karsten, Cai, Zhiming, Wang, Jun, Gui, Yaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764820/
https://www.ncbi.nlm.nih.gov/pubmed/26907467
http://dx.doi.org/10.1038/srep21831

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