Simultaneous knockdown of uPA and MMP9 can reduce breast cancer progression by increasing cell-cell adhesion and modulating EMT genes

In cancer progression, proteolytic enzymes like serine proteases and metalloproteinases degrade the basement membrane enabling the tumor cells to invade the adjacent tissues. Thus, invasion and metastasis are augmented by these enzymes. Simultaneous silencing of uPA and MMP9 in breast cancer cells d...

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Detalles Bibliográficos
Autores principales: Moirangthem, Anuradha, Bondhopadhyay, Banashree, Mukherjee, Mala, Bandyopadhyay, Arghya, Mukherjee, Narendranath, Konar, Karabi, Bhattacharya, Shubham, Basu, Anupam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764826/
https://www.ncbi.nlm.nih.gov/pubmed/26906973
http://dx.doi.org/10.1038/srep21903

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