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Production of hepatitis E virus-like particles presenting multiple foreign epitopes by co-infection of recombinant baculoviruses
Hepatitis E virus (HEV) causes not only endemics via a fecal-oral route but also sporadic cases via zoonotic transmission or blood transfusion. HEV-like particles (HEV-LP) produced by using a baculovirus expression system are considered a candidate for mucosal vaccines for HEV infection. In this stu...
Autores principales: | Shima, Ryoichi, Li, Tian Cheng, Sendai, Yutaka, Kataoka, Chikako, Mori, Yoshio, Abe, Takayuki, Takeda, Naokazu, Okamoto, Toru, Matsuura, Yoshiharu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764844/ https://www.ncbi.nlm.nih.gov/pubmed/26905478 http://dx.doi.org/10.1038/srep21638 |
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