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Drug activity screening based on microsomes-hydrogel system in predicting metabolism induced antitumor effect of oroxylin A
A novel microsomes-hydrogel added cell culture system (MHCCS) was employed in the antitumor activity screening of natural compounds, aiming to achieve drug screening with better in vivo correlation, higher initiative to explore the potential active metabolites, and investigation of the antitumor mec...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764850/ https://www.ncbi.nlm.nih.gov/pubmed/26905263 http://dx.doi.org/10.1038/srep21604 |