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Intracellular delivery of antibodies by chimeric Sesbania mosaic virus (SeMV) virus like particles

The therapeutic potential of antibodies has not been fully exploited as they fail to cross cell membrane. In this article, we have tested the possibility of using plant virus based nanoparticles for intracellular delivery of antibodies. For this purpose, Sesbania mosaic virus coat protein (CP) was g...

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Detalles Bibliográficos
Autores principales: Abraham, Ambily, Natraj, Usha, Karande, Anjali A., Gulati, Ashutosh, Murthy, Mathur R. N., Murugesan, Sathyabalan, Mukunda, Pavithra, Savithri, Handanahal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764859/
https://www.ncbi.nlm.nih.gov/pubmed/26905902
http://dx.doi.org/10.1038/srep21803

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