Development of Spexin-based Human Galanin Receptor Type II-Specific Agonists with Increased Stability in Serum and Anxiolytic Effect in Mice

The novel neuropeptide spexin (SPX) was discovered to activate galanin receptor 2 (GALR2) and 3 (GALR3) but not galanin receptor 1 (GALR1). Although GALR2 is known to display a function, particularly in anxiety, depression, and appetite regulation, the further determination of its function would ben...

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Detalles Bibliográficos
Autores principales: Reyes-Alcaraz, Arfaxad, Lee, Yoo-Na, Son, Gi Hoon, Kim, Nam Hoon, Kim, Dong-Kyu, Yun, Seongsik, Kim, Dong-Hoon, Hwang, Jong-Ik, Seong, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764904/
https://www.ncbi.nlm.nih.gov/pubmed/26907960
http://dx.doi.org/10.1038/srep21453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764904/
https://www.ncbi.nlm.nih.gov/pubmed/26907960
http://dx.doi.org/10.1038/srep21453

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