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A Novel Method to Simulate the Progression of Collagen Degeneration of Cartilage in the Knee: Data from the Osteoarthritis Initiative
We present a novel algorithm combined with computational modeling to simulate the development of knee osteoarthritis. The degeneration algorithm was based on excessive and cumulatively accumulated stresses within knee joint cartilage during physiological gait loading. In the algorithm, the collagen...
Autores principales: | Mononen, Mika E., Tanska, Petri, Isaksson, Hanna, Korhonen, Rami K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764929/ https://www.ncbi.nlm.nih.gov/pubmed/26906749 http://dx.doi.org/10.1038/srep21415 |
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