Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart

The leading cause of death in diabetic patients is diabetic cardiomyopathy, in which alteration of Akt signal plays an important role. Inpp5f is recently found to be a negative regulator of Akt signaling, while its expression and function in diabetic heart is largely unknown. In this study, we found...

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Detalles Bibliográficos
Autores principales: Bai, Danna, Zhang, Yajun, Shen, Mingzhi, Sun, Yongfeng, Xia, Qing, Zhang, Yingmei, Liu, Xuedong, Wang, Haichang, Yuan, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764951/
https://www.ncbi.nlm.nih.gov/pubmed/26908121
http://dx.doi.org/10.1038/srep22068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764951/
https://www.ncbi.nlm.nih.gov/pubmed/26908121
http://dx.doi.org/10.1038/srep22068

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