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Effects of warm ischemia and reperfusion on the liver microcirculatory phenotype of rats: underlying mechanisms and pharmacological therapy

Warm ischemia and reperfusion (WIR) causes hepatic damage and may lead to liver failure, however the mechanisms involved are largely unknown. Here we have characterized the microcirculatory status and endothelial phenotype of livers undergoing WIR, and evaluated the use of simvastatin in WIR injury...

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Detalles Bibliográficos
Autores principales: Hide, Diana, Ortega-Ribera, Martí, Garcia-Pagan, Juan-Carlos, Peralta, Carmen, Bosch, Jaime, Gracia-Sancho, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764954/
https://www.ncbi.nlm.nih.gov/pubmed/26905693
http://dx.doi.org/10.1038/srep22107