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Effects of warm ischemia and reperfusion on the liver microcirculatory phenotype of rats: underlying mechanisms and pharmacological therapy
Warm ischemia and reperfusion (WIR) causes hepatic damage and may lead to liver failure, however the mechanisms involved are largely unknown. Here we have characterized the microcirculatory status and endothelial phenotype of livers undergoing WIR, and evaluated the use of simvastatin in WIR injury...
Autores principales: | Hide, Diana, Ortega-Ribera, Martí, Garcia-Pagan, Juan-Carlos, Peralta, Carmen, Bosch, Jaime, Gracia-Sancho, Jordi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764954/ https://www.ncbi.nlm.nih.gov/pubmed/26905693 http://dx.doi.org/10.1038/srep22107 |
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