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Antithrombotic and antiplatelet activities of small-molecule alkaloids from Scolopendra subspinipes mutilans

The aim of this study was to discover small-molecule anticoagulants from Scolopendra subspinipes mutilans (SSM). A new acylated polyamine (1) and a new sulfated quinoline alkaloid (2) were isolated from SSM. Treatment with the new alkaloids 1, 2, and indole acetic acid 4 prolonged the activated part...

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Detalles Bibliográficos
Autores principales: Lee, Wonhwa, Lee, JungIn, Kulkarni, Roshan, Kim, Mi-Ae, Hwang, Jae Sam, Na, MinKyun, Bae, Jong-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764974/
https://www.ncbi.nlm.nih.gov/pubmed/26905699
http://dx.doi.org/10.1038/srep21956