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AZD8797 is an allosteric non-competitive modulator of the human CX3CR1 receptor
The chemokine receptor CX(3)CR1 has been implicated as an attractive therapeutic target in several diseases, including atherosclerosis and diabetes. However, there has been a lack of non-peptide CX(3)CR1 inhibitors to substantiate these findings. A selective small-molecule inhibitor of CX(3)CR1, AZD...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764977/ https://www.ncbi.nlm.nih.gov/pubmed/26656484 http://dx.doi.org/10.1042/BJ20150520 |