The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma

Expression of the SS18/SYT-SSX fusion protein is believed to underlie the pathogenesis of synovial sarcoma (SS). Recent evidence suggests that deregulation of the Wnt pathway may play an important role in SS but the mechanisms whereby SS18-SSX might affect Wnt signaling remain to be elucidated. Here...

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Detalles Bibliográficos
Autores principales: Cironi, Luisa, Petricevic, Tanja, Fernandes Vieira, Victor, Provero, Paolo, Fusco, Carlo, Cornaz, Sandrine, Fregni, Giulia, Letovanec, Igor, Aguet, Michel, Stamenkovic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764983/
https://www.ncbi.nlm.nih.gov/pubmed/26905812
http://dx.doi.org/10.1038/srep22113

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