Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure

ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in both chronic and acute heart failu...

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Detalles Bibliográficos
Autores principales: Villacorta, Humberto, Maisel, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765013/
https://www.ncbi.nlm.nih.gov/pubmed/26761075
http://dx.doi.org/10.5935/abc.20150151
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author Villacorta, Humberto
Maisel, Alan S.
author_facet Villacorta, Humberto
Maisel, Alan S.
author_sort Villacorta, Humberto
collection PubMed
description ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in both chronic and acute heart failure. It is a new biomarker that meets all required criteria for a useful biomarker. Of note, it adds information to natriuretic peptides (NPs) and some studies have shown it is even superior in terms of risk stratification. Since the introduction of NPs, this has been the most promising biomarker in the field of heart failure and might be particularly useful as therapy guide.
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spelling pubmed-47650132016-02-26 Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure Villacorta, Humberto Maisel, Alan S. Arq Bras Cardiol Review Article ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis. Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in both chronic and acute heart failure. It is a new biomarker that meets all required criteria for a useful biomarker. Of note, it adds information to natriuretic peptides (NPs) and some studies have shown it is even superior in terms of risk stratification. Since the introduction of NPs, this has been the most promising biomarker in the field of heart failure and might be particularly useful as therapy guide. Sociedade Brasileira de Cardiologia - SBC 2016-02 /pmc/articles/PMC4765013/ /pubmed/26761075 http://dx.doi.org/10.5935/abc.20150151 Text en http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Villacorta, Humberto
Maisel, Alan S.
Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_full Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_fullStr Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_full_unstemmed Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_short Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
title_sort soluble st2 testing: a promising biomarker in the management of heart failure
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765013/
https://www.ncbi.nlm.nih.gov/pubmed/26761075
http://dx.doi.org/10.5935/abc.20150151
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