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The paralog-to-contig assignment problem: high quality gene models from fragmented assemblies

BACKGROUND: The accurate annotation of genes in newly sequenced genomes remains a challenge. Although sophisticated comparative pipelines are available, computationally derived gene models are often less than perfect. This is particularly true when multiple similar paralogs are present. The issue is...

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Detalles Bibliográficos
Autores principales: Indrischek, Henrike, Wieseke, Nicolas, Stadler, Peter F., Prohaska, Sonja J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765045/
https://www.ncbi.nlm.nih.gov/pubmed/26913054
http://dx.doi.org/10.1186/s13015-016-0063-y