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Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression
Expression quantitative trait loci (eQTL) mapping is a widely used tool to study the genetics of gene expression. Confounding factors and the burden of multiple testing limit the ability to map distal trans eQTLs, which is important to understand downstream genetic effects on genes and pathways. We...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765046/ https://www.ncbi.nlm.nih.gov/pubmed/26911988 http://dx.doi.org/10.1186/s13059-016-0895-2 |