Double-blind, 12 month follow-up, placebo-controlled trial of mifepristone on cognition in alcoholics: the MIFCOG trial protocol

BACKGROUND: Increased levels of cortisol during acute alcohol withdrawal have been linked to cognitive deficits and depression. Preclinical research found that the glucocorticoid Type II receptor antagonist, mifepristone, prevented some of the neurotoxic effects of withdrawal and memory loss. Clinic...

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Detalles Bibliográficos
Autores principales: Donoghue, Kim, Rose, Abigail, Coulton, Simon, Milward, Joanna, Reed, Kylie, Drummond, Colin, Little, Hilary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765152/
https://www.ncbi.nlm.nih.gov/pubmed/26912003
http://dx.doi.org/10.1186/s12888-016-0757-1

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