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Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma

BACKGROUND: Growing evidence is showing that metastatic cell populations are able to transfer their characteristics to less malignant cells. Exosomes (EXOs) are membrane vesicles of endocytic origin able to convey their cargo of mRNAs, microRNAs (miRs), proteins and lipids from donors to proximal as...

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Detalles Bibliográficos
Autores principales: Felicetti, Federica, De Feo, Alessandra, Coscia, Carolina, Puglisi, Rossella, Pedini, Francesca, Pasquini, Luca, Bellenghi, Maria, Errico, Maria Cristina, Pagani, Elena, Carè, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765208/
https://www.ncbi.nlm.nih.gov/pubmed/26912358
http://dx.doi.org/10.1186/s12967-016-0811-2