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Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C
The liver biopsy has long been the "gold standard" for assessing liver fibrosis in patients with hepatitis C. It's an invasive procedure which is associated with an elevated bleeding, especially in chronic hemodialysis patients. Main goal is to assess liver fibrosis in chronic hemodia...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765332/ https://www.ncbi.nlm.nih.gov/pubmed/26958136 http://dx.doi.org/10.11604/pamj.2015.22.273.2311 |
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author | Arrayhani, Mohamed Sqalli, Tarik Tazi, Nada El Youbi, Randa Chaouch, Safae Aqodad, Nourdin Ibrahimi, Sidi Adil |
author_facet | Arrayhani, Mohamed Sqalli, Tarik Tazi, Nada El Youbi, Randa Chaouch, Safae Aqodad, Nourdin Ibrahimi, Sidi Adil |
author_sort | Arrayhani, Mohamed |
collection | PubMed |
description | The liver biopsy has long been the "gold standard" for assessing liver fibrosis in patients with hepatitis C. It's an invasive procedure which is associated with an elevated bleeding, especially in chronic hemodialysis patients. Main goal is to assess liver fibrosis in chronic hemodialysis with HCV by Fibroscan and by biological scores (APRI, Forns and Fib-4), and to measure the correlation between these tests. Cross-sectional study including all chronic hemodialysis patients with hepatitis C virus, in two public hemodialysis centers of Fez. All patients were evaluated for liver fibrosis using noninvasive methods (FibroScan and laboratory tests). Subsequently, the correlation between different tests has been measured. 95 chronic hemodialysis were studied, twenty nine patients (30.5%) with chronic hepatitis C. The average age was 52.38 ± 16.8 years. Nine liver fibrosis cases have been concluded by forns score. Fibroscan has objectified significant fibrosis in 6 cases. On the other side APRI has objectified sgnifivant fibrosis only in 3 cases. The Fib-4 showed severe fibrosis in five cases. The results have been most consistent between APRI and Fib-4, followed by Fibroscan and Forns, then APRI and FibroScan. |
format | Online Article Text |
id | pubmed-4765332 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-47653322016-03-08 Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C Arrayhani, Mohamed Sqalli, Tarik Tazi, Nada El Youbi, Randa Chaouch, Safae Aqodad, Nourdin Ibrahimi, Sidi Adil Pan Afr Med J Case Series The liver biopsy has long been the "gold standard" for assessing liver fibrosis in patients with hepatitis C. It's an invasive procedure which is associated with an elevated bleeding, especially in chronic hemodialysis patients. Main goal is to assess liver fibrosis in chronic hemodialysis with HCV by Fibroscan and by biological scores (APRI, Forns and Fib-4), and to measure the correlation between these tests. Cross-sectional study including all chronic hemodialysis patients with hepatitis C virus, in two public hemodialysis centers of Fez. All patients were evaluated for liver fibrosis using noninvasive methods (FibroScan and laboratory tests). Subsequently, the correlation between different tests has been measured. 95 chronic hemodialysis were studied, twenty nine patients (30.5%) with chronic hepatitis C. The average age was 52.38 ± 16.8 years. Nine liver fibrosis cases have been concluded by forns score. Fibroscan has objectified significant fibrosis in 6 cases. On the other side APRI has objectified sgnifivant fibrosis only in 3 cases. The Fib-4 showed severe fibrosis in five cases. The results have been most consistent between APRI and Fib-4, followed by Fibroscan and Forns, then APRI and FibroScan. The African Field Epidemiology Network 2015-11-23 /pmc/articles/PMC4765332/ /pubmed/26958136 http://dx.doi.org/10.11604/pamj.2015.22.273.2311 Text en © Mohamed Arrayhani et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Arrayhani, Mohamed Sqalli, Tarik Tazi, Nada El Youbi, Randa Chaouch, Safae Aqodad, Nourdin Ibrahimi, Sidi Adil Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C |
title | Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C |
title_full | Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C |
title_fullStr | Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C |
title_full_unstemmed | Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C |
title_short | Non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis C |
title_sort | non invasive assessment of liver fibrosis in chronic hemodialysis patients with viral hepatitis c |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765332/ https://www.ncbi.nlm.nih.gov/pubmed/26958136 http://dx.doi.org/10.11604/pamj.2015.22.273.2311 |
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