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Open Sesame: treasure in store-operated calcium entry pathway for cancer therapy
Store-operated Ca(2+) entry (SOCE) controls intracellular Ca(2+) homeostasis and regulates a wide range of cellular events including proliferation, migration and invasion. The discovery of STIM proteins as Ca(2+) sensors and Orai proteins as Ca(2+) channel pore forming units provided molecular tools...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765918/ https://www.ncbi.nlm.nih.gov/pubmed/25481035 http://dx.doi.org/10.1007/s11427-014-4774-3 |