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Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APC(Min/+) Mouse Model of Intestinal Tumorigenesis

Nonsteroidal anti-inflammatory drugs have been shown to reduce the incidence of gastrointestinal cancers, but the propensity of these drugs to cause ulcers and bleeding limits their use. H(2)S has been shown to be a powerful cytoprotective and anti-inflammatory substance in the digestive system. Thi...

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Detalles Bibliográficos
Autores principales:	Paul-Clark, Mark, Elsheikh, Wagdi, Kirkby, Nicholas, Chan, Melissa, Devchand, Pallavi, Agbor, Terence A., Flannigan, Kyle L., Cheadle, Charlotte, Freydin, Maxim, Ianaro, Angela, Mitchell, Jane A., Wallace, John L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766010/ https://www.ncbi.nlm.nih.gov/pubmed/26910063 http://dx.doi.org/10.1371/journal.pone.0147289

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