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Hyperthermic Laser Ablation of Recurrent Glioblastoma Leads to Temporary Disruption of the Peritumoral Blood Brain Barrier

BACKGROUND: Poor central nervous system penetration of cytotoxic drugs due to the blood brain barrier (BBB) is a major limiting factor in the treatment of brain tumors. Most recurrent glioblastomas (GBM) occur within the peritumoral region. In this study, we describe a hyperthemic method to induce t...

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Detalles Bibliográficos
Autores principales: Leuthardt, Eric C., Duan, Chong, Kim, Michael J., Campian, Jian L., Kim, Albert H., Miller-Thomas, Michelle M., Shimony, Joshua S., Tran, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766093/
https://www.ncbi.nlm.nih.gov/pubmed/26910903
http://dx.doi.org/10.1371/journal.pone.0148613

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