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Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice

The cardiac hormone atrial natriuretic peptide (ANP) regulates systemic and pulmonary arterial blood pressure by activation of its cyclic GMP-producing guanylyl cyclase-A (GC-A) receptor. In the lung, these hypotensive effects were mainly attributed to smooth muscle-mediated vasodilatation. It is un...

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Detalles Bibliográficos
Autores principales:	Werner, Franziska, Kojonazarov, Baktybek, Gaßner, Birgit, Abeßer, Marco, Schuh, Kai, Völker, Katharina, Baba, Hideo A., Dahal, Bhola K., Schermuly, Ralph T., Kuhn, Michaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766231/ https://www.ncbi.nlm.nih.gov/pubmed/26909880 http://dx.doi.org/10.1007/s00395-016-0541-x

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